Toxic Epidermal Necrolysis

Condition Overview

Toxic epidermal necrolysis is a rare, ulcerative skin disease that appears to be triggered by various drugs, internal cancers, infections, and unknown factors.

Symptoms

Blebs (an irregular bulge in the plasma membrane of a cell), ulcers, and erosions develop suddenly and progress rapidly. The mouth and foot pads are frequently involved. This is an extremely painful disease. The dog is severely depressed and refuses to eat. The fatality rate approaches 30%

All symptoms +

Causes

This condition appears to be triggered by various drugs, internal cancers, infections, and unknown factors.

Diagnosis

Diagnosis is made by physical examination.

Treatment

Treatment involves stopping all suspect medications and correcting and underlying cause. Corticosteroids, intravenous fluids, and antibiotics are required during the acute phase of the illness to support the circulation. Recovery takes 2 - 3 weeks.

Prevention

There is currently no known prevention for this condition.

Support

Please contact your veterinarian if you think your pet may have this condition.