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208 Breeds, 422 Health Conditions  |  Find a Vet

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Pulmonary Infiltrates of Eosinophils

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Condition Overview

Pulmonary Infiltrates of Eosinophils (PIE) is an uncommon respiratory disease in dogs, caused by the presence of numerous eosinophils (a type of white blood cell) in the blood, respiratory secretions, and lungs.

Symptoms

Signs of PIE are fever, cough rapid breathing, and weight loss, Listening to the chest with a stethoscope reveals dry, crackling sounds. The diagnosis is made by finding eosinophils in the blood and transtracheal washings.

Causes

Eosinophils usually indicate a hypersensitivity reaction. Accordingly, an allergic basis for PIE has been proposed. The source of the allergy is ususally unknown.

Diagnosis

Before a diagnosis of PIE can be made, other causes of eosinophilia, such as heartworms, lungworms, migrating intestinal parasites, fungal infections, and lymphosarcoma, must be excluded.

Treatment

Treatment involves large doses of corticosteroids that are tapered off gradually over several weeks. many dogs recover fully, but relapses can occur.

Prevention

There is no prevention for this condition.

Support

Please contact your veterinarian with questions regarding this condition.

Show Sources & Contributors +

Sources

Dog Owners Home Veterinary Handbook

Publisher: Wiley Publishing, 2007

Website: http://www.wiley.com/WileyCDA/

Authors: Debra M. Eldredge, Liisa D. Carlson, Delbert G. Carlson, James M. Giffen MD

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